Common variable immunodeficiency. The first case in Granma province

Authors

  • Reynel Marrón González Centro Médico Ambulatorio del Hospital General Docente Carlos Manuel de Céspedes. Bayamo. Granma
  • Bárbara de la Caridad Addine Ramírez Filial de Ciencias Médicas Dr. Efraín Benítez Popa. Bayamo. Granma

Keywords:

immune system disease, common variable immunodeficiency, IgA's deficiency, agammaglobulinemia, aged.

Abstract

Common variable immunodeficiency is considered the phenotypic expression of a set of genetic defects of the immune system with complex hereditary patterns. Its manifestations are related to the loss or diminution in the functions of the B lymphocytes. It is a primary immunodeficiency, can debut in adulthood and concomitant with allergic diseases, autoimmune or some neoplastic diseases and in particular there can exist personal and familiar pathological antecedents of deficit of IgA. Its main clinical manifestations are associated with frequent infectious diseases, with a poor evolution and low serum levels of all immunoglobulin isotypes. The case of a patient with this disease, who comes to the consultation referred by the service of rheumatology with presence of articular pains and decay, is consulted. With the use of the clinical method and the immunological studies that showed the presence of values in 0 in two immunoglobulin isotypes and very low in one case, the disease was diagnosed and other studies were carried out.

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References

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Published

2018-01-17

How to Cite

1.
Marrón González R, Addine Ramírez B de la C. Common variable immunodeficiency. The first case in Granma province. RM [Internet]. 2018 Jan. 17 [cited 2025 Jun. 3];21(6). Available from: https://revmultimed.sld.cu/index.php/mtm/article/view/686

Issue

Vol. 21 No. 6 (2017)

Section

CASOS CLÍNICOS

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