Risk factors for moderate to severe migraine disability
Keywords:
risk factors, migraine disorders, sleep wake disorders, case-control studies, nausea, anxiety.Abstract
Introduction: migraine is the seventh cause of work, domestic and social disability in the world and is the main cause of disability among neurological conditions. Factors associated with the degree of migraine disability have been little studied.
Objective: to identify risk factors with independent influence on moderate to severe migraine disability.
Method: a case-control study was conducted in patients with migraine. The sample size was calculated using the EpiDat 3.0 program. The final sample consisted of 104 patients with moderate to severe disability (cases) and 208 patients with mild to moderate disability (controls).
Results: it was observed that the frequency of days with headaches in the previous three months increased the risk of moderate to severe disability by more than 24 times (OR- 24.24; 95 % CI- 8.10-72.46), have associated other patterns of headache almost doubled the risk (OR- 9.04; 95 % CI- 3.75-21.80) and having a poor sleep quality increased sextupled (OR- 6.06; 95 % CI- 2.29-16.06). Moderate or intense phonophobia (OR- 4.99; 95 % CI- 2.06-12.09); frequent nausea (OR 3.24 95% CI 1.29-8.11); pathological anxiety (OR- 3.06; 95 % CI- 1.28-7.34); the abuse of analgesics (OR- 2.95 95 % CI- 1.26-6.88 and depression (OR- 2.79; 95 % CI- 1.09-7.21) also behaved as risk factors.
Conclusions: the most important independent influencing risk factors for moderate to severe migraine disability were the frequency of headaches, associated headache patterns, poor sleep quality, and moderate or severe phonophobia.
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References
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