Guillain-Barre Syndrome in the Intensive Care Unit

Authors

  • Juan Carlos Fonseca Muñoz Hospital Provincial Carlos Manuel de Céspedes. Bayamo. Granma
  • Adonis Frómeta Guerra Hospital Provincial Carlos Manuel de Céspedes. Bayamo. Granma
  • Tamara Alicia Fonseca Muñoz Filial de Ciencias Médicas. Bayamo. Granma
  • Juan Ernesto Pizarro Ojea Hospital Provincial Carlos Manuel de Céspedes. Bayamo. Granma
  • Daily Silveira Sánchez Policlínico Docente 13 de Marzo. Bayamo. Granma

Keywords:

guillain-barre syndrome/epidemiology, guillain-barre syndrome/complications.

Abstract

It was performed a descriptive and retrospective study of patients with a diagnosis of Guillain-Barré Syndrome which were hospitalized in the Intensive Care Unit  of the University Hospital "Carlos Manuel de Cespedes" from January 1st, 2005 to December 31, 2008, with the aim of identifying the present clinical and epidemiological aspects. 28 patients were included, 53.6% between 30 and 44 years old and 64.3% of the male sex. The 50.0% of them presented antecedents of upper respiratory tract infection. The predominant motor symptoms were the capture of upper and lower extremities with 11 cases (39.3%). The treatment with Intaglobín was implemented in 19 patients (67.9%). The complications were presented by 42.9%.  35.7% needed mechanical ventilation and 57.1 % had to stay 15 days or more at the hospital. The majority of cases graduated alive without motor sequels of the service (60.7%). It was concluded that the disease predominated in young male patients. The antecedents of upper respiratory infections, motor symptoms and treatment were more common with Intaglobín. Acute respiratory failure and bacterial-bronchopneumonia were predominant complications. The majority of cases graduated alive without motor sequels, although the stay was prolonged in them.

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References

1.Chio A, Cocito D, Leone M, Giordana MT, Mora G, Mutani R. Register for Guillain Barre Syndrome: a prospective, population-based incidence and outcome survey. Neurology 2003;60 (7):1146-50.

2.Pritchard J, Hughes R. Guillain-Barré syndrome.Lancet. 2004;363:2186-8.

3.Schleicher G, Black A, Mochan A, Richards GA. Effect of human immunodeficiency virus on intensive care unit outcome of patients with Guillain Barre syndrome. Crit Care Med 2003;31(6):1848-50.

4.Hughes Richard AC, Comblath David R. Guillain Barre Syndrome. Lancet 2005; 366:1653-66.

5.Hughes Richard AC, Swan Anthony V, van Doorn Pieter A. Corticosteroids for Guillain-Barré syndrome. Cochrane Database of Systematic Reviews. In: The Cochrane Library [Internet] 2011 [citado 22 abril 2011]; (12); [aprox. 7p.] Disponible en: http://cochrane.bvsalud.org/cochrane/show.php?db=reviews&mfn=759&id=CD001446&lang=es&dblang=&lib=COC

6.Sharar E. Current therapeutic options in severe Guillain-Barre syndrome. Clin Neuropharmacol. 2006 Jan-Feb; 29 (1):45-51.

7.Guerra Verdecia C, Rodríguez Cañete AR, Millán Vegal M, Fajardo Tornes YL. Síndrome de Guillain-Barré-Strohl y embarazo. Presentación de 1 caso y revisión de la entidad. Rev Cubana Obstet Ginecol [Internet].2001[citado 10 de marzo 2011]; 27 (2): [aprox. 5p.] disponible en: http://bvs.sld.cu/revistas/gin/vol27_2_01/gin10201.htm

8.Los Trastornos del Sistema Nervioso. El Síndrome de Guillain-Barré. [Internet] 2006 [citado14 de abril 2011];38(6): [aprox.6p.] disponible en: http://es.wikipedia.org/w/index.php?title=S%C3%ADndrome_de_Guillain-Barr%

9.Ortiz-Corredor F, Mieth-Alviar KW. Factores pronósticos para la marcha en el síndrome de Guillan-Barré infantil. Rev Neurol.[Internet] 2003 [citado 20 de diciembre 2011]; 36(12): [aprox.9p.] disponible en: http://bvs.sld.cu/revistas/gin/vol27_2_01/gin10201.htm

10.National Institute of Neurological Disorders and Stroke. El Síndrome de Guillain-Barré.[Internet] 2006 [citado 17 de julio 2006]; 42(3): [aprox. 3p] disponible en: http://www.ninds.nih.gov/disorders/spanish/el_sindrome_de_guillain_barre.htm#que

11. Enciclopedia médica en español. Síndrome de Guillain-Barré.[Internet] 2007 [citado 26 de mayo 2011]; 32(5): [aprox. 7p] disponible en: http://www.nlm.nih.gov/medlineplus/spanish/ency/article/000684.htm

12.Ashbury, AK. Nuevos conceptos sobre el Síndrome de Guillain Barre. J Neurol. 2000; 15:183-91.

13.Valls JS, CAsademont JP, Berciano BD. Enfermedades de los nervios periféricos. En: Farreras VP, Rozman CR, eds. Medicina Interna. Madrid, Harcourt SA; 2000. p 1753-70.

14.Roca Goderich R. Polineuropatías. En: temas de Medicina Interna. Ciencias Médicas: La Habana; 2002. p.477-80.

15.Hahn AF: The Challenge of Respiratory Dysfuntion in Guillain-Barré Syndrome. Arch Neurol Vol 58, June 2001. 871.

16.Wiles CM, Brown P, Chapel H. Intravenous immunoglobulin in neurological disease: a specialist review. J Neurol Neurosurg Psychiatry. [Internet] 2002 [citado 12 de abril 2011]; 72(4): [aprox. 8p.] Disponible en: http://jnnp.bmj.com/content/72/4/440.short

17.Hernández Almeida E, Balíp Dip David, Cruz Batista MR, Moreno Ramírez O. Presentación clínica y evolución del síndrome de Guillain-Barré em uma unidad de cuidados intensivos. Rev Cubana Med. [Internet] 2002 [citado 11 de mayo 2011];41(6):[aprox.8p.]Disponible en: http://scielo.sld.cu/scielo.php?pid=S0034-75232002000600007&script=sci_arttext&tlng=es

18.Chroni E, Thomopoulos C, Papapetropoulos S, Paschalis C, Karatza CL. A case of relapsing Guillain Barre Syndrome associated with exacerbation of chronic hepatitis B virus hepatitis. N Engl J Med 2004;350(11):1118-29.

19.Chamonuni P, Tamion F, Gueit I, Girault C, Lenain P, Varin R. Adverse effect of polyvalent inmunoglobulin in the treatment of Guillain Barre syndrome. Transfus Apheresis Sci 2003;(2):117-24.

20.Inoue N, Kunishige M, Yoshino H, Oshima Y, Ohnishi Y, Kuroda Y. Dissociation between titer of anti-ganglioside antibody and severity of symptoms in a case of Guillain-Barre syndrome with treatment related fluctuation. J Neurol Sci 2003;210(12):105-8.

Published

2017-07-05

How to Cite

1.
Fonseca Muñoz JC, Frómeta Guerra A, Fonseca Muñoz TA, Pizarro Ojea JE, Silveira Sánchez D. Guillain-Barre Syndrome in the Intensive Care Unit. RM [Internet]. 2017 Jul. 5 [cited 2025 Jun. 3];16(1):54-68. Available from: https://revmultimed.sld.cu/index.php/mtm/article/view/516

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Section

ARTÍCULOS ORIGINALES