Hemolytic disease of the newborn by isoimmunization to minor blood groups. A weird case

Authors

  • Rafael Ferrer Montoya Hospital Provincial Carlos Manuel de Céspedes. Bayamo. Granma, Cuba.
  • Belkys Cecilia Laurenzo González Hospital Pediátrico José Luis Miranda. Villa Clara, Cuba.
  • Elmer Armando Ávila Sánchez Hospital Pediátrico Octavio de la Concepción de la Pedraja. Holguín, Cuba.

Keywords:

fetal erythroblastosis, anemia, hemolytic, jaundice.

Abstract

Hemolytic disease of the fetus and the newborn is an isoimmune immunologic disease, frequently seen in cases of ABO incompatibility groups, less frequent in Rh groups incompatibility cases and they are even less frequent in cases on incompatibility to minor blood groups. We report the case of an 8 days old female newborn with blood group and Rh compatible to her mother, transferred to our hospital because of jaundice with serum levels of high bilirrubin and severe anemia. Before the hematological research it was carried out the phototherapy and also blood transfusions. Later studies confirmed that the hemolytic anemia and jaundice were due to irregular anti-bodies anti C and anti Cw. The hemolysis decreased gradually, the evolution of the newborn was favorable and the patient was discharged with a normal hematic byometry and without any further problems. This case reminds us that with the declination of the hemolytic anemia due to Rh incompatibility, it has to be taken into consideration the jaundice and secondary hemolysis to unusual or minor groups.

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References

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Published

2016-07-20

How to Cite

1.
Ferrer Montoya R, Laurenzo González BC, Ávila Sánchez EA. Hemolytic disease of the newborn by isoimmunization to minor blood groups. A weird case. RM [Internet]. 2016 Jul. 20 [cited 2025 Jun. 1];20(3):623-9. Available from: https://revmultimed.sld.cu/index.php/mtm/article/view/205

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Section

ARTÍCULOS ORIGINALES