Humoral immunodeficiencies in children 1-5 years old. Main infectious diseases associated. Granma. 2012-2017

Authors

  • Bárbara de la Caridad Addine Ramírez Filial de Ciencias Médicas Dr. Efraín Benítez Popa. Bayamo. Granma
  • Reynel Marrón González Centro Médico Ambulatorio, Hospital General Docente Carlos M. Céspedes. Bayamo. Granma
  • Misella Reyes Fajardo Filial de Ciencias Médicas Dr. Efraín Benítez Popa. Bayamo. Granma
  • Ramón Luis Fonseca González Filial de Ciencias Médicas Dr. Efraín Benítez Popa. Bayamo. Granma

Keywords:

immune system disease, humoral immunity, IgA deficiency, agammaglobulinemia, communicable diseases

Abstract

Immunodeficiencies are a set of diseases by qualitative or quantitative alterations in the components of the immune system, whose main clinical manifestation is the association with infectious diseases. Knowing the behaviour of humoral immunodeficiencies and associated infections contribute to the correct diagnosis and treatment of patients, to the correct planning of expensive resources and to maintain adequate vaccination coverage. An analytical study of cases and controls was carried out at the Granma Ambulatory Medical Center from 2012 to 2017, aimed at describing the behaviour of humoral immunodeficiencies in children aged 1-5 years and their association with infectious diseases. The sample consisted of 156 patients, 52 with immunodeficiencies, considered cases and 104 without immunodeficiencies that made up the control group. Age, sex, presence of allergies, associated infections and frequency of appearance of humoral immunodeficiencies were analysed. The statistical processing included descriptive statistics, making use of summary measures for qualitative variables. Chi-square and odds ratio tests with a significance level of 5 % were used to identify the association between variables. Among the immunodeficient individuals of 2 years and the male sex predominated. The most frequent immunodeficiency was IgA deficiency. Age was not associated with the possibility of suffering from different types of immunodeficiency. Among the associated infectious diseases, pneumonias and otitis were the most common. The common cold was not associated with immunodeficiencies.

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Published

2018-05-03

How to Cite

1.
Addine Ramírez B de la C, Marrón González R, Reyes Fajardo M, Fonseca González RL. Humoral immunodeficiencies in children 1-5 years old. Main infectious diseases associated. Granma. 2012-2017. RM [Internet]. 2018 May 3 [cited 2025 Aug. 16];22(2):403-22. Available from: https://revmultimed.sld.cu/index.php/mtm/article/view/842

Issue

Vol. 22 No. 2 (2018)

Section

ARTÍCULOS ORIGINALES

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