Giant virilizing tumor of left ovarian granulose cells. Clinical case

Authors

  • Adolfo Luis Malcolm Suárez Hospital General Docente Universitario Carlos Manuel de Céspedes. Bayamo.
  • Gricel Liliana Díaz Juan Hospital General Docente Universitario Carlos Manuel de Céspedes. Bayamo.
  • Dayana Leyva Fonseca Facultad de Ciencias Médicas Efraín Pompa Benítez. Bayamo.

Keywords:

Peripheral tumors, Virilization, Granulose cells.

Abstract

Peripheral steroid-producing tumors are rare entities and are potentially malignant. Testosterone is the most commonly elevated hormone and is mostly associated with signs of virilization. A case of a 62-year-old patient with a giant virilizing ovarian granulose cell tumor was diagnosed. Scheduled laparotomy was performed with freezing biopsy and total abdominal hysterectomy with double anixectomy plus omentectomy. I evolve favorably without complications. The case reported here is that of a patient with a history of apparent health, regular menstruations, with an obstetric history of 4 gestations and having been operated on at 24 years of a fetal heart rate, before a table of virilization syndrome were used data from hospital medical history, complementary examinations, interview and physical examination of the patient. Despite the time of evolution presented by the patient with the giant virilizing tumor of cells of the left ovary granulose, the operation was a success and the evolution has been satisfactory, thanks to the work of the medical staff who were in charge of the case, demonstrating once again the strengths of the Cuban health system in situations like these.

Downloads

Download data is not yet available.

References

1. Huerta Sáenz I. Criterios sonogáficos de evaluación de malignidad de tumores de ovario Metodología IOTA (International Ovarian Tumor Analysis Group). Rev Peru Ginecol Obstet 2019; 65(3): 311-315.

2. Jacobs IJ, Menon U, Ryan A, Gentry-Maharaj A, Burnell M, Kalsi JK, et al. Ovarian cancer screen-ing and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a ran-domised controlled trial. Lancet 2016; 387(10022): 945-56.

3. Timmerman D, Van Calster B, Testa AC, Savelli L, Fischerova D, Froyman W, et al. Predict-ing the risk of malignancy in adnexal masses based on the Simple Rules from the International Ovarian Tumor Analysis group. Am J Obstet Gynecol 2016; 214(4): 424-437.

4. Li YK. CT imaging of ovarian yolk sac tumor with emphasis on differential diagnosis. Sci Rep [Internet]. 2015 [citado 2/8/2019]; 5. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466583/

5. Cai-Yan L. Clinical experience of uterine tumors resembling ovarian sex cord tumors: a clinic pathological analysis of 6 cases. Int J Clin Exp Pathol 2015; 8(4): 4158-4164.

6. Spinelli C, Pucci V, Strambi S, Lo Piccolo R, Martin A, Messineo A. Treatment of ovarian lesions in children and adolescents: a retrospective study of 130 cases. Pediatr Hematol Oncol 2015; 32(3): 199-206.

7. Spinelli C, Strambi S, Liloia C, Bertocchini A, Messineo A. Update on the surgical management of ovarian neoplasms in children and adolescents: analysis on 32 cases. Gynecol Endocrinol 2016; 32(10): 787-91.

8. Mariampillai AI, Cruz JPD, Suh J, Sivapiragasam A, Nevins K, Hindenburg AA. Cancer Antigen 72-4 for the Monitoring of Advanced Tumors of the Gastrointestinal Tract, Lung, Breast and Ovaries. Anticancer Res 2017; 37(7): 3649-56.

9. Abbas PI, Dietrich JE, Francis JA, Brandt ML, Cass DL, Lopez ME. Ovarian-sparing surgery in pediatric benign ovarian tumors. J Pediatr Adolesc Gynecol 2016; 29(5): 506-10.

10. Blake EA, Sheridan TB, Wang KL, Takiuchi T, Kodama M. Clinical characteristics and outcomes of uterine tumors resembling ovarian sex-cord tumors (UTROSCT): a systematic review of literature. Eur J ObstetGynecolReprod Biol 2014; 181: 163–170.

11. Instituto Nacional del Cáncer. Tratamiento de los tumores extragonadales de células germinativas (PDQ®). Instituto Nacional del Cáncer. [Internet]. 2014 [Citado 5/8/2019]. Disponible en: https://www.cancer.gov/espanol/tipos/extragonadal-celulas-germinativas/pro/tratamiento-extragonadal-pdq

Downloads

Published

2020-10-15

How to Cite

1.
Malcolm Suárez AL, Díaz Juan GL, Leyva Fonseca D. Giant virilizing tumor of left ovarian granulose cells. Clinical case. RM [Internet]. 2020 Oct. 15 [cited 2025 Jul. 14];24(5). Available from: https://revmultimed.sld.cu/index.php/mtm/article/view/2081

Issue

Vol. 24 No. 5 (2020)

Section

CASOS CLÍNICOS

License

Avisos de derechos de autor propuestos por Creative Commons

1. Política propuesta para revistas que ofrecen acceso abierto

Aquellos autores/as que tengan publicaciones con esta revista, aceptan los términos siguientes:
  1. Los autores/as conservarán sus derechos de autor y garantizarán a la revista el derecho de primera publicación de su obra, el cuál estará simultáneamente sujeto a la Licencia de reconocimiento de Creative Commons que permite a terceros compartir la obra siempre que se indique su autor y su primera publicación esta revista.
  2. Los autores/as podrán adoptar otros acuerdos de licencia no exclusiva de distribución de la versión de la obra publicada (p. ej.: depositarla en un archivo telemático institucional o publicarla en un volumen monográfico) siempre que se indique la publicación inicial en esta revista.
  3. Se permite y recomienda a los autores/as difundir su obra a través de Internet (p. ej.: en archivos telemáticos institucionales o en su página web) antes y durante el proceso de envío, lo cual puede producir intercambios interesantes y aumentar las citas de la obra publicada. (Véase El efecto del acceso abierto).